The Power of Vitamin B12: Why Your Body, and Brain, Depend on It

At Refresh & Renew MedSpa in Clarkston, MI, we see more and more people struggling with low energy, poor focus or that constant sense of running on empty. Often, the culprit isn’t lack of sleep or caffeine withdrawal, it’s Vitamin B12 deficiency.

Vitamin B12 (also known as cobalamin) is one of the most essential nutrients for your overall health. It powers cellular metabolism, supports brain and nerve function, and helps produce red blood cells that carry oxygen throughout your body. Yet, studies show that up to 16% of healthy adults between 26 and 49 are already deficient, even without obvious symptoms.

That’s why at Refresh & Renew, we offer Vitamin B12 IM injections using methylcobalamin, the most bioactive form of B12—so your body can absorb and use it immediately.

Mitochondria are th powerhouse of the cell. Vitamin B12 helps support its production of energy (ATP).

Energy Production and Cellular Metabolism

Vitamin B12 plays a key role in converting food into usable energy through the metabolism of carbohydrates, fats and proteins. When levels are low, your mitochondria (your cells’ powerhouses) struggle to produce ATP, the molecule responsible for fueling everything from brain activity to muscle contractions.

Methylcobalamin supports this process efficiently, which is why clients often report increased energy, improved endurance and reduced fatigue within days of their injection.

Brain Health and Cognitive Function

Your brain and nervous system depend heavily on Vitamin B12 for proper function. It supports myelin formation, the protective sheath around nerve cells that allows smooth, fast communication between brain and body.

Research has shown that low B12 levels are linked to cognitive decline and increased risk of dementia. In a long-term Finnish study of elderly participants, those with B12 deficiencies had a significantly higher likelihood of developing Alzheimer’s disease compared to those with healthy levels.

Regular supplementation with methylcobalamin helps protect memory, mental clarity and focus—especially important as we age.

Mood Regulation and Stress Response

Vitamin B12 works closely with folate and vitamin B6 to regulate homocysteine, an amino acid that can accumulate when B12 levels are low. Elevated homocysteine is linked not only to cardiovascular disease but also to mood disorders, anxiety and depression.

By balancing these pathways, B12 injections help support neurotransmitter production, including serotonin and dopamine, leading to improved mood stability and stress resilience.

Cardiovascular and Muscular Health

Healthy B12 levels are associated with lower homocysteine, improved blood flow and reduced risk of stroke. In one study of more than 43,000 men followed for 14 years, those with normal B12 levels had a significantly decreased risk of ischemic stroke.

Because B12 supports oxygen transport and muscle metabolism, deficiency can also contribute to weakness, shortness of breath and slower recovery from exercise or illness. IM injections replenish these stores efficiently, helping your body perform and recover at its best.

ntramuscular injection allows the vitamin to be maximally absorbed and immediately used.

Why Injections Work Better Than Oral Supplements

Absorbing B12 through the digestive tract depends on a protein called intrinsic factor, produced in the stomach. But many adults—especially those taking acid-blockers, metformin or who’ve had gastric surgery—can’t produce enough of it. That means oral B12 often passes through the system unused.

Intramuscular methylcobalamin injections bypass the gut entirely, delivering the vitamin directly into the bloodstream for maximum absorption and efficacy.

How Often Should You Get a B12 Injection?

For most clients, we recommend a Vitamin B12 injection every monthly to maintain healthy energy levels and neurological support. Those with known deficiencies or chronic fatigue may benefit from more frequent injections initially.

The Refresh & Renew Difference

Our intramuscular (IM) injections use the form of Vitamin B12 called methylcobalamin, the purest and most effective form of B12 available. Whether you’re managing fatigue, supporting recovery or simply optimizing your health, this treatment helps restore vitality from the inside out.

B12 injections can be added to any appointment or you can visit us at Iron24 in Lake Orion, Michigan, the second Wednesday every month for a complimentary B12 Injection. Book your appointment today at Refresh & Renew MedSpa in Clarkston, MI, and experience the difference that true cellular energy can make.